One Health Solution for a Sustainable Future of Antibiotic Resistance in the Food Chain

Abstract

The food chain has become a silent accomplice in the spread of antibiotic resistance (AMR), jeopardizing our ability to treat life-threatening infections and ensure food security. Excessive antibiotic use in food animals, often for routine prophylaxis and growth promotion, drives the emergence and spread of resistant bacteria, contaminating meat, and the environment, and potentially reaching human consumers. This research tackles this complex challenge through a multi-pronged One Health approach, recognizing the interconnectedness of human, animal, and environmental health. We propose investigating the prevalence of AMR in food-producing animals and retail meat within a specific region while piloting a One Health intervention strategy combining antibiotic-enhanced food chain hygiene, public awareness, and education. Quantify the prevalence of AMR in food animals and retail meat within the chosen region. Develop and test an educational program for farmers and veterinarians on antibiotic stewardship practices, evaluating its impact on antibiotic use and resistance levels. Assess the economic feasibility and sustainability of implementing alternative strategies for antibiotics in a specific food and animal sector. By rigorously investigating the effectiveness of these interventions and their impact on reducing antibiotic use, resistant bacteria prevalence, and transmission to humans. Antibiotic resistance in the food chain is becoming a major concern for global health and food security. By overcoming obstacles such as political commitment, multi-sector collaboration, and alternative antibiotic research, we can harness the potential of One Health to preserve human and animal health, secure our food supply, and guarantee antibiotics remain effective disease-fighting tools in the years ahead.